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Evidences of role of physical traumas, friction, oxidative stress and MIA in non-segmental vitiligo

Posted by Robot on October 29, 2014 at 9:22am in Main

Hi Friends,

I've just created this discussion to provide evidences (papers,  sources,  books, whatsoever) regarding the major role that physical traumas, friction, oxidative stress and MIA (melanoma inhibitory activity)  play in vitiligo disease.  They are the cause / consequence of the non-segmental vitiligo (effect).

Whoever is interested in, please let me know that I will provide all necessary medical papers.  

Please only join this discussion if you really want to read the stuff.  Many thanks.

 

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Replies

  • Alchemist November 15, 2014 at 6:40pm

    Thanks for initiating this interesting thread. Tenascins are associated with a range of diseases including brain and breast cancers, but not much is known about their functions. Tenascin-C for example is overexpressed in some tumor tissues and is a potential target for tumor therapy. It would be really interesting to see whether knocking down Tenascin-C has any effect on vitiligo lesions. This can be done using siRNA in animal models as reference 9 suggests. I am curious to know whether any research group has ever explored this possibility. This seems like a very interesting line of research.

  • Steve Hargadon November 14, 2014 at 11:41am

    This is a terrific service.  Thanks, Flavio.

  • Felicia Durr November 12, 2014 at 3:54pm

    Thanks for sharing this wealth of information.

  • Robot November 12, 2014 at 12:25pm

    One more doc.

    Study of CCN3 (NOV) and DDR1 in normal melanocytes and vitiligo ski...

  • Robot November 3, 2014 at 3:43pm

    Document 9.

    Another interesting doc.

    Authors: Anuschirwan Peyman, Eugen Uhlmann,Caroline Weiser

    oligonucleotides against tenascin for treating vitiligo.url

  • Robot November 2, 2014 at 1:06pm

    Document 8.

    Tenascin overexpressed in vitiligo

    Authors: Le Poole and P.K.Das

    tenascin.pdf

  • Robot October 31, 2014 at 12:59pm

    Going to the second round, now it's time to talk in depth about melanocyte integrin. Please read Document 7 attached. The whole idea will be covered when we get to Document 12. Attachments:

    Role of integrins in melanocyte attachment and dendricity.pdf

  • Robot October 31, 2014 at 12:32pm

    Going to the second round, now it's time to talking in depth about melanocyte integrin.

    Please read Document 7 attached.

    The whole idea will be covered when we get to Document 12.

  • rajanikanth October 31, 2014 at 4:15am
    Thank you very much for all your hard work
This reply was deleted.